St. Paul's Senior High School or St. Paul's Boys College (SPACO), formerly St. Paul's Secondary, is a Ghanaian boys' senior high school located at Hatsukope-Denu in the Ketu South Municipal Assembly of the Volta Region.

Established in 1958, it is a Catholic school that is part of the Roman Catholic Diocese of Keta–Akatsi and has a minor seminary attached to it.[1][2] The school has the nickname SPACO derived from its name, however, the alumni (the old student's union) call themselves Conquerors.